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What is pneumococcal disease?

This section will provide you with an understanding of the causes and consequences of pneumococcal disease, as well as its burden on children and their families. Studies show that:

  • One child out of every five who contracts pneumococcal meningitis will die2, 3.

Prior to the addition of the pneumococcal conjugate vaccine to the UK's routine childhood immunisation schedule:

  • Pneumococcal meningitis was the UK's second most common cause of bacterial meningitis2, 3.
  • An estimated 50 children under five died from pneumococcal disease in the UK every year1.
  • 1 out of every 200 children in the UK were hospitalised before their 5th birthday due to pneumococcal pneumonia4.
  • By the age of three years, nearly all children will have experienced at least one episode of otitis media and half of them will get another within two years5.

Pneumococcal meningitis is among the most destructive forms of bacterial meningitis in the UK (after meningitis B)2,3 and is among the most destructive in terms of death and permanent disability6,7. One child out of every five who contracts the disease will die2,3, while half of those who survive will be left with some level of disability ranging from brain damage to deafness6. Pneumonia caused by the pneumo bug can occur much more often than pneumonia caused by other bugs and many children have to see their GP or go to hospital because of it4,8.

  1. Derived from McIntosh EDG, Booy R. Invasive pneumococcal diseases in England and Wales: what is the true burden and what is the potential for prevention using 7-valent pneumococcal conjugate vaccine? Arch Dis Child 2002; 86:403-406.
  2. Chief Medical Officer, DoH. Preventing Meningitis; http://www.dh.gov.uk/ AboutUs/ MinistersAndDepartmentLeaders/ ChiefMedicalOfficer/ ProgressOnPolicy/ ProgressBrowsableDocument/fs/en?CONTENT_ID=4102788& MULTIPAGE_ID=5389535&chk=Uq8NtA
  3. Ispahani P et al. Twenty year surveillance of invasive pneumococcal disease in Nottingham: serogroups responsible and implications for immunisation. Arch Dis Child 2004; 89: 757-762.
  4. Djuretic T et al. Hospital admissions in children due to pneumococcal pneumonia in England. J of Inf 1998; 37:54-58.
  5. Rovers MM et al. Otitis Media. Lancet 2004; 363: 465-73
  6. Baraff L et al. Outcomes of bacterial meningitis in children: a meta-analysis. Paed Infect Dis J 1993; 12:389-394.
  7. Bedford H et al. Meningitis in infancy in England and Wales: follow up at age 5 years. BMJ 2001; 323: 1-5.
  8. Miller, E et al. Epidemiology of invasive and other pneumococcal disease in children in England and Wales 1996-1998. Acta Paed Suppl 2000; 435: 11-16.
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